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ICSI (Intra-Cytoplasmic Sperm Injection)

What is ICSI?

Intracytoplasmic sperm injection, or ICSI, involves injecting a single live sperm directly into the centre of a human egg. The procedure overcomes many of the barriers to fertilization and allows couples with little hope of achieving a successful pregnancy to obtain fertilized embryos.

How is ICSI performed?

The video shows the process of Intra-Cytoplasmic Sperm Injection (ICSI). The egg is held in place while a single sperm is injected into the cytoplasm of the egg using a fine needle.

Who should consider ICSI?

ICSI is considered absolutely necessary is in the case of male factor infertility with an abnormal semen analysis. Male infertility factors can include any of the following:

Low sperm counts

Poor motility or movement of the sperm

Poor sperm quality

Sperm that lack the ability to penetrate an egg

Azoospermia

This is a condition where there is no sperm in the male’s ejaculation. In these cases, sperm may be extracted from testis or epididymis and can be used to fertilize eggs using ICSI technics (See TESA / ICSI)

Also, some patients may choose to undergo ICSI for reasons other than male factor infertility, including:

Previous poor fertilization with IVF

Unexplained infertility

Patient going for PGT (Preimplantation Genetic Testing)